UniProt Q86UT5
NA(+)/H(+) exchange regulatory cofactor nhe-RF4 (Q86UT5)
NA(+)/H(+) exchange regulatory cofactor nhe-RF4 (UniProt Q86UT5): 2 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86UT5
- Protein
- NA(+)/H(+) exchange regulatory cofactor nhe-RF4
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
3 records of Q86UT5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V90 | Crystal structure of the 3rd PDZ domain of intestine- and kidney- enriched PDZ domain IKEPP (PDZD3) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2V90 | Crystal structure of the 3RD PDZ domain of intestine- and kidney- enriched PDZ domain ikepp (PDZD3) | x-ray diffraction | A, B, C, D, E, F | — | — |
| Q86UT5 | AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF4 (Q86UT5) | predicted | A | — | 11 (best 0.60) |
Experiment against prediction
- 2V90 chain C against the predicted model Q86UT5: TM-score 0.85, RMSD 1.56 Å
- 2V90 chain C against the predicted model Q86UT5: TM-score 0.85, RMSD 1.56 Å
- 2V90 chain A against the predicted model Q86UT5: TM-score 0.85, RMSD 1.66 Å
- 2V90 chain A against the predicted model Q86UT5: TM-score 0.85, RMSD 1.66 Å
Elsewhere
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