UniProt Q86TM3
Probable ATP-dependent RNA helicase DDX53 (Q86TM3)
Probable ATP-dependent RNA helicase DDX53 (UniProt Q86TM3), EC 3.6.4.13: 3 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86TM3
- Protein
- Probable ATP-dependent RNA helicase DDX53
- EC
- 3.6.4.13
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
4 records of Q86TM3 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3IUY | Crystal structure of DDX53 DEAD-box domain | x-ray diffraction | A, B | — | — |
| 3IUY | Crystal structure of DDX53 dead-box domain | x-ray diffraction | A, B | — | — |
| 8KCA | Crystal structure of DDX53 helicase domain | x-ray diffraction | A, B | — | 3 (best 0.56) |
| Q86TM3 | AlphaFold monomer V2.0 prediction for probable ATP-dependent RNA helicase DDX53 (Q86TM3) | predicted | A | — | — |
Experiment against prediction
- 3IUY chain A against the predicted model Q86TM3: TM-score 0.99, RMSD 0.57 Å
- 3IUY chain A against the predicted model Q86TM3: TM-score 0.99, RMSD 0.57 Å
- 3IUY chain B against the predicted model Q86TM3: TM-score 0.99, RMSD 0.64 Å
- 3IUY chain B against the predicted model Q86TM3: TM-score 0.99, RMSD 0.64 Å
- 8KCA chain B against the predicted model Q86TM3: TM-score 0.96, RMSD 1.05 Å
- 8KCA chain A against the predicted model Q86TM3: TM-score 0.94, RMSD 1.29 Å
Elsewhere
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