UniProt Q86SQ0
Pleckstrin homology-like domain family B member 2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (UniProt Q86SQ0): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q86SQ0
- Protein
- Pleckstrin homology-like domain family B member 2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
4 records of Q86SQ0 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8WHJ | Crystal structure of CLASP2 TOG4 fused with LL5beta | x-ray diffraction | A | CL | 1 (best 0.51) |
| 8WHK | Crystal structure of CLASP2 in complex with LL5beta | x-ray diffraction | B | — | 2 (best 0.44) |
| 8WHM | Crystal structure of the ELKS2/LL5beta complex | x-ray diffraction | B | — | — |
| Q86SQ0 | AlphaFold monomer V2.0 prediction for pleckstrin homology-like domain family B member 2 (Q86SQ0) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 1 record
Experiment against prediction
- 8WHJ chain A against the predicted model O75122: TM-score 0.89, RMSD 0.95 Å
- 8WHK chain B against the predicted model Q86SQ0: TM-score 0.75, RMSD 1.74 Å
- 8WHM chain B against the predicted model Q86SQ0: TM-score 0.70, RMSD 2.05 Å
- 8WHJ chain A against the predicted model Q86SQ0: TM-score 0.25, RMSD 6.01 Å
Elsewhere
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