UniProt Q86DA5
NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1 (Q86DA5)
NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1 (UniProt Q86DA5), EC 3.2.2.-, 3.2.2.6: 3 experimental structures on GenesisL1, 1 ligand bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q86DA5
- Protein
- NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1
- EC
- 3.2.2.-, 3.2.2.6
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 40 · 2 records with a druggable one
Structures
3 records of Q86DA5 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8P2L | A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain. | electron microscopy | A, B, C, D, E, F, G, H, J, I, K, L, M, N, O, P | NAD | 20 (best 0.79) |
| 8P2M | C. elegans TIR-1 protein. | electron microscopy | A, B, C, D, E, F, G, H, I | — | 20 (best 0.76) |
| Q86DA5 | AlphaFold monomer V2.0 prediction for NAD(+) hydrolase tir-1 (Q86DA5) | — | — | — |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 1 record
Elsewhere
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