UniProt Q84TH5
ABC transporter G family member 25 (Q84TH5)
ABC transporter G family member 25 (UniProt Q84TH5): 15 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 196 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q84TH5
- Protein
- ABC transporter G family member 25
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 196 · 15 records with a druggable one
Structures
16 records of Q84TH5 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8I38 | Cryo-EM structure of abscisic acid transporter AtABCG25 in inward conformation | electron microscopy | A, B | — | 8 (best 0.83) |
| 8I39 | Cryo-EM structure of abscisic acid transporter AtABCG25 with ABA | electron microscopy | A, B | A8S | 10 (best 0.84) |
| 8I3A | Cryo-EM structure of abscisic acid transporter AtABCG25 in outward conformation | electron microscopy | A, B | ATP, MG | 19 (best 0.83) |
| 8I3B | Cryo-EM structure of abscisic acid transporter AtABCG25 in nanodisc | electron microscopy | A, B | ATP | 17 (best 0.86) |
| 8I3C | Cryo-EM structure of abscisic acid transporter AtABCG25 with CHS | electron microscopy | A, B | Y01 | 16 (best 0.85) |
| 8I3D | Cryo-EM structure of abscisic acid transporter AtABCG25 | electron microscopy | A, B | — | 14 (best 0.82) |
| 8IWJ | ABCG25 Wild Type in Apo-state | electron microscopy | A, B | — | 9 (best 0.83) |
| 8IWK | ABCG25 Wild Type purified with DDM plus CHS in ABA-bound state | electron microscopy | A, C | A8S | 13 (best 0.84) |
| 8IWN | ABCG25 EQ mutant in ATP-bound state | electron microscopy | A, C | ATP, MG | 16 (best 0.86) |
| 8K0X | ABCG25 Wild Type purified with DDM in the ABA-bound state | electron microscopy | A, C | A8S | 10 (best 0.84) |
| 8K0Z | ABCG25 Wild Type purified with DDM in the apo-state | electron microscopy | A, B | — | 10 (best 0.83) |
| 8WAM | Cryo-EM structure of the ABCG25 E232Q mutant bound to ATP and Magnesium | electron microscopy | A, B | ATP, MG | 20 (best 0.81) |
| 8WBA | Cryo-EM structure of the ABCG25 bound to CHS | electron microscopy | A, B | Y01 | 10 (best 0.84) |
| 8WBX | Cryo-EM structure of the ABCG25 bound to ABA | electron microscopy | A, B | A8S | 12 (best 0.83) |
| 8WD6 | Cryo-EM structure of the ABCG25 | electron microscopy | A, B | — | 12 (best 0.82) |
| Q84TH5 | AlphaFold monomer V2.0 prediction for ABC transporter G family member 25 (Q84TH5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8WBX chain B against the predicted model Q84TH5: TM-score 0.98, RMSD 1.16 Å
- 8WBX chain A against the predicted model Q84TH5: TM-score 0.98, RMSD 1.20 Å
- 8WBA chain A against the predicted model Q84TH5: TM-score 0.97, RMSD 1.35 Å
- 8WBA chain B against the predicted model Q84TH5: TM-score 0.97, RMSD 1.35 Å
- 8I39 chain A against the predicted model Q84TH5: TM-score 0.97, RMSD 1.48 Å
- 8I39 chain B against the predicted model Q84TH5: TM-score 0.97, RMSD 1.48 Å
- 8I38 chain A against the predicted model Q84TH5: TM-score 0.97, RMSD 1.51 Å
- 8I38 chain B against the predicted model Q84TH5: TM-score 0.97, RMSD 1.51 Å
- 8I3D chain B against the predicted model Q84TH5: TM-score 0.96, RMSD 1.67 Å
- 8I3D chain A against the predicted model Q84TH5: TM-score 0.96, RMSD 1.67 Å
Elsewhere
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