UniProt Q7ZCI0
Protease (Q7ZCI0)
Protease (UniProt Q7ZCI0): 14 experimental structures on GenesisL1, 4 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7ZCI0
- Protein
- Protease
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 5 · 5 records with a druggable one
Structures
14 records of Q7ZCI0 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DH0 | Crystal structure of HIV-1 Protease NL4-3 I84V Mutant in complex with darunavir | x-ray diffraction | B, A | 017 | 1 (best 0.73) |
| 6DH0 | Crystal structure of HIV-1 protease NL4-3 I84V mutant in complex with darunavir | x-ray diffraction | B, A | 017 | — |
| 6DH1 | Crystal structure of HIV-1 Protease NL4-3 I84V Mutant in complex with UMass1 | x-ray diffraction | B, A | SO4, K13 | 1 (best 0.73) |
| 6DH1 | Crystal structure of HIV-1 protease NL4-3 I84V mutant in complex with UMASS1 | x-ray diffraction | B, A | SO4, K13 | — |
| 6DH2 | Crystal structure of HIV-1 Protease NL4-3 I84V Mutant in complex with UMass6 | x-ray diffraction | B, A | SO4, A60 | 1 (best 0.74) |
| 6DH2 | Crystal structure of HIV-1 protease NL4-3 I84V mutant in complex with UMASS6 | x-ray diffraction | B, A | SO4, A60 | — |
| 6OPT | HIV-1 Protease NL4-3 V82F, I84V Mutant in complex with darunavir | x-ray diffraction | B, A | 017, SO4 | 1 (best 0.73) |
| 6OPT | HIV-1 protease NL4-3 V82F, I84V mutant in complex with darunavir | x-ray diffraction | B, A | 017, SO4 | — |
| 6OPU | HIV-1 protease NL4-3 K45I, M46I, V82F, I84V mutant in complex with darunavir | x-ray diffraction | B, A | 017 | — |
| 6OPV | HIV-1 protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, V82F, I84V mutant in complex with darunavir | x-ray diffraction | B, A | 017 | — |
| 6OPW | HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, V82F, I84V Mutant in complex with… | x-ray diffraction | B, A | SO4, 017 | 1 (best 0.74) |
| 6OPW | HIV-1 protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, V82F, I84V mutant in complex with… | x-ray diffraction | B, A | SO4, 017 | — |
| 6OPX | HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, L76V, V82F, I84V Mutant in complex with… | x-ray diffraction | B, A | 017 | — |
| 6OPX | HIV-1 protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, L76V, V82F, I84V mutant in complex with… | x-ray diffraction | B, A | 017 | — |
Ligands
- 017 · (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate · in 10 records
- SO4 · Sulfate ion · in 8 records
- A60 · (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate · in 2 records
- K13 · (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-benzyl-2-hydroxypropyl]carbamate · in 2 records
Elsewhere
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