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UniProt Q7Z721

RPS6KB1 protein (Q7Z721)

RPS6KB1 protein (UniProt Q7Z721): 14 experimental structures on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q7Z721
Protein
RPS6KB1 protein
Experimental structures
14
Predicted models
0
Ligands
3
Pockets
23 · 7 records with a druggable one

Structures

14 records of Q7Z721 in the MolNFT archive: 14 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4L3JCrystal structures of human p70S6K1 kinase domainx-ray diffractionA5FI, ZN3 (best 0.73)
4L3JCrystal structures of human P70S6K1 kinase domainx-ray diffractionA——
4L3LCrystal structures of human p70S6K1 kinase domain (Zinc anomalous)x-ray diffractionA5FI, ZN3 (best 0.75)
4L3LCrystal structures of human P70S6K1 kinase domain (zinc anomalous)x-ray diffractionA——
4L42Crystal structures of human p70S6K1-PIFx-ray diffractionA5FI, SO4, ZN3 (best 0.72)
4L42Crystal structures of human P70S6K1-pifx-ray diffractionA——
4L43Crystal structures of human p70S6K1-T389A (form I)x-ray diffractionA5FI4 (best 0.75)
4L43Crystal structures of human P70S6K1-T389A (form I)x-ray diffractionA——
4L44Crystal structures of human p70S6K1-T389A (form II)x-ray diffractionASO4, 5FI, ZN1 (best 0.78)
4L44Crystal structures of human P70S6K1-T389A (form II)x-ray diffractionA——
4L45Crystal structures of human p70S6K1-T389Ex-ray diffractionA5FI5 (best 0.76)
4L45Crystal structures of human P70S6K1-T389Ex-ray diffractionA——
4L46Crystal structures of human p70S6K1-WTx-ray diffractionA5FI, SO4, ZN4 (best 0.75)
4L46Crystal structures of human P70S6K1-wtx-ray diffractionA——

Ligands

  • 5FI · 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole · in 7 records
  • ZN · Zinc ion · in 5 records
  • SO4 · Sulfate ion · in 3 records

Elsewhere

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