UniProt Q7Z5Q5
DNA polymerase nu (Q7Z5Q5)
DNA polymerase nu (UniProt Q7Z5Q5), EC 2.7.7.7: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7Z5Q5
- Protein
- DNA polymerase nu
- EC
- 2.7.7.7
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
9 records of Q7Z5Q5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XVI | Binary complex of human polymerase nu and DNA with the finger domain ajar | x-ray diffraction | A | — | — |
| 4XVI | Binary complex of human polymerase nu and DNA with the finger domain ajar | x-ray diffraction | A | — | — |
| 4XVK | Binary complex of human polymerase nu and DNA with the finger domain closed | x-ray diffraction | A | NA | 9 (best 0.74) |
| 4XVK | Binary complex of human polymerase nu and DNA with the finger domain closed | x-ray diffraction | A | — | — |
| 4XVL | Binary complex of human polymerase nu and DNA with the finger domain open | x-ray diffraction | A | — | — |
| 4XVL | Binary complex of human polymerase nu and DNA with the finger domain open | x-ray diffraction | A | — | — |
| 4XVM | Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain… | x-ray diffraction | A | — | — |
| 4XVM | Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain… | x-ray diffraction | A | — | — |
| Q7Z5Q5 | AlphaFold monomer V2.0 prediction for DNA polymerase nu (Q7Z5Q5) | predicted | A | — | — |
Ligands
- NA · Sodium ion · in 1 record
Experiment against prediction
- 4XVI chain A against the predicted model Q7Z5Q5: TM-score 0.99, RMSD 0.83 Å
- 4XVI chain A against the predicted model Q7Z5Q5: TM-score 0.99, RMSD 0.83 Å
- 4XVL chain A against the predicted model Q7Z5Q5: TM-score 0.99, RMSD 1.07 Å
- 4XVL chain A against the predicted model Q7Z5Q5: TM-score 0.99, RMSD 1.07 Å
- 4XVK chain A against the predicted model Q7Z5Q5: TM-score 0.98, RMSD 1.27 Å
- 4XVK chain A against the predicted model Q7Z5Q5: TM-score 0.98, RMSD 1.27 Å
- 4XVM chain A against the predicted model Q7Z5Q5: TM-score 0.91, RMSD 3.21 Å
- 4XVM chain A against the predicted model Q7Z5Q5: TM-score 0.91, RMSD 3.21 Å
Elsewhere
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