UniProt Q7Z4V5
Hepatoma-derived growth factor-related protein 2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (UniProt Q7Z4V5): 38 experimental structures on GenesisL1, 32 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7Z4V5
- Protein
- Hepatoma-derived growth factor-related protein 2
- Experimental structures
- 38
- Predicted models
- 0
- Ligands
- 32
- Pockets
- 20 · 0 records with a druggable one
Structures
38 records of Q7Z4V5 in the MolNFT archive: 38 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3EAE | PWWP domain of human hepatoma-derived growth factor 2 (HDGF2) | x-ray diffraction | A, B | — | — |
| 3EAE | Pwwp domain of human hepatoma-derived growth factor 2 (HDGF2) | x-ray diffraction | A, B | — | — |
| 3QBY | Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2 | x-ray diffraction | A, B, C | — | — |
| 3QBY | Crystal structure of the pwwp domain of human hepatoma-derived growth factor 2 | x-ray diffraction | A, B, C | — | — |
| 3QJ6 | The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with… | x-ray diffraction | A | — | — |
| 3QJ6 | The crystal structure of pwwp domain of human hepatoma-derived growth factor 2 in complex with… | x-ray diffraction | A | — | — |
| 6T3I | Solution structure of the HRP2 ibd | solution nmr | A | — | — |
| 7HG1 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, UWS | — |
| 7HG2 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1H97, U0S | — |
| 7HG4 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, UXG | 1 (best 0.42) |
| 7HG5 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, WV4 | 1 (best 0.45) |
| 7HG7 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with Z46169164 | x-ray diffraction | A, B, C | SO4, EJQ | — |
| 7HG8 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, VZP | 1 (best 0.44) |
| 7HG9 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A3Q | 1 (best 0.45) |
| 7HGE | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with Z45527714 | x-ray diffraction | A, B, C | SO4, X0S | 1 (best 0.47) |
| 7HGF | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, T0Y | — |
| 7HGG | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A4B | 1 (best 0.39) |
| 7HGI | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with Z57475068 | x-ray diffraction | A, B, C | SO4, A1A35 | — |
| 7HGJ | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, ZUG | 1 (best 0.44) |
| 7HGM | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1AM1 | 1 (best 0.46) |
| 7HGO | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, 8DH | 1 (best 0.42) |
| 7HGR | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1AM6 | — |
| 7HGS | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1AMX | 1 (best 0.46) |
| 7HGT | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A3R | 1 (best 0.43) |
| 7HGU | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, VVJ | 1 (best 0.41) |
| 7HGX | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A31 | — |
| 7HH3 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A3X | — |
| 7HH7 | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, LJR | — |
| 7HHC | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with Z31432964 | x-ray diffraction | A, B, C | SO4, SYX | — |
| 7HHI | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1H9V | 1 (best 0.44) |
| 7HHK | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, LPU | 2 (best 0.44) |
| 7HHO | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1H9U | — |
| 7HHP | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with Z31723394 | x-ray diffraction | A, B, C | SO4, A1A3Z | 1 (best 0.46) |
| 7HHQ | PanDDA analysis group deposition -- Crystal structure of HRP-2 PWWP domain in complex with… | x-ray diffraction | A, B, C | SO4, A1A3Y | — |
| 9GRS | Crystal structure of HRP-2 PWWP domain in complex with compound 8 | x-ray diffraction | A, B, C | SO4, A1H6Y | 1 (best 0.42) |
| 9GRT | Crystal structure of HRP-2 PWWP domain in complex with compound 29 | x-ray diffraction | A, B, C | BYZ, SO4 | 1 (best 0.28) |
| 9GRU | Crystal structure of HRP-2 PWWP domain in complex with compound 30 | x-ray diffraction | A, B, C | PYZ, SO4 | 2 (best 0.47) |
| Q7Z4V5 | AlphaFold monomer V2.0 prediction for hepatoma-derived growth factor- related protein 2 (Q7Z4V5) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 30 records
- 8DH · N-methyl-3-oxo-N-(propan-2-yl)piperazine-1-sulfonamide · in 1 record
- A1A31 · (2R)-1-(2-methyl-1H-imidazol-1-yl)propan-2-ol · in 1 record
- A1A35 · N~1~,N~1~,N~4~,N~4~-tetramethylpiperazine-1,4-dicarboxamide · in 1 record
- A1A3Q · N-{(1R)-1-[(4S)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}acetamide · in 1 record
- A1A3R · (2S,5R)-4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]-2,5-dimethylmorpholine · in 1 record
- A1A3X · 2-[(2S)-2-methylpiperidin-1-yl]ethan-1-amine · in 1 record
- A1A3Y · 2-(2,2-dimethylpyrrolidin-1-yl)ethan-1-amine · in 1 record
- A1A3Z · N,N-diethyl-2-methylbenzamide · in 1 record
- A1A4B · [(2R)-2-methylpiperidin-1-yl](4-methyl-1,3-thiazol-5-yl)methanone · in 1 record
- A1AM1 · N-{[(4R)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}propanamide · in 1 record
- A1AM6 · 2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine · in 1 record
- A1AMX · (2R)-2-ethyl-N,N-dimethylmorpholine-4-sulfonamide · in 1 record
- A1H6Y · 1-bromanyl-4-methylsulfonyl-benzene · in 1 record
- A1H97 · (5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane · in 1 record
- A1H9U · ~{N}-(3-azanyl-2-methyl-phenyl)propanamide · in 1 record
- A1H9V · ~{N},~{N}-dimethyl-1~{H}-pyrazole-4-sulfonamide · in 1 record
- BYZ · 4-bromo-1H-pyrazole · in 1 record
- EJQ · ~{N}-(4-fluorophenyl)-2-pyrrolidin-1-yl-ethanamide · in 1 record
- LJR · 1-cyclohexyl-N-methylmethanesulfonamide · in 1 record
- LPU · 1-(methanesulfonyl)piperidin-4-ol · in 1 record
- PYZ · 4-iodopyrazole · in 1 record
- SYX · (4-methylpiperazin-1-yl)[(2R)-oxolan-2-yl]methanone · in 1 record
- T0Y · 1-[(thiophen-3-yl)methyl]piperidin-4-ol · in 1 record
- U0S · (5S)-7-(pyrazin-2-yl)-2-oxa-7-azaspiro[4.4]nonane · in 1 record
- UWS · 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one · in 1 record
- UXG · 1-(diphenylmethyl)azetidin-3-ol · in 1 record
- VVJ · N-cycloheptyl-N-methylmethanesulfonamide · in 1 record
- VZP · N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]-N-methyl-N'-propan-2-ylurea · in 1 record
- WV4 · N-ethyl-2-fluoro-4-(methylsulfonyl)aniline · in 1 record
Elsewhere
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