UniProt Q7Z434
Mitochondrial antiviral-signaling protein (Q7Z434)
Mitochondrial antiviral-signaling protein (UniProt Q7Z434): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 97 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q7Z434
- Protein
- Mitochondrial antiviral-signaling protein
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 97 · 9 records with a druggable one
Structures
18 records of Q7Z434 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MS7 | High-resolution solid-state NMR structure of the helical signal transduction filament MAVS CARD | solid-state nmr | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U | — | 20 (best 0.91) |
| 2MS7 | High-resolution solid-state NMR structure of the helical signal transduction filament mavs card | solid-state nmr | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U | — | — |
| 2MS8 | Solution NMR structure of MAVS CARD | solution nmr | A | — | — |
| 2MS8 | Solution NMR structure of mavs card | solution nmr | A | — | — |
| 2VGQ | Crystal Structure of Human IPS-1 CARD | x-ray diffraction | A | GLC, SO4 | 4 (best 0.70) |
| 2VGQ | Crystal structure of human ips-1 card | x-ray diffraction | A | GLC, SO4 | 4 (best 0.70) |
| 3J6C | Cryo-EM structure of MAVS CARD filament | electron microscopy | A | — | — |
| 3J6C | Cryo-EM structure of mavs card filament | electron microscopy | A | — | — |
| 3J6J | 3.6 Angstrom resolution MAVS filament generated from helical reconstruction | electron microscopy | A, B, C, D, E, G, I, L | — | 9 (best 0.88) |
| 3J6J | 3.6 ångström resolution mavs filament generated from helical reconstruction | electron microscopy | A, B, C, D, E, G, I, L | — | 9 (best 0.88) |
| 4P4H | Caught-in-action signaling complex of RIG-I 2CARD domain and MAVS CARD domain | x-ray diffraction | I, J, K, L, N, O, P, M | — | 9 (best 0.91) |
| 4P4H | Caught-in-action signaling complex of rig-I 2CARD domain and mavs card domain | x-ray diffraction | I, J, K, L, N, O, P, M | — | 9 (best 0.91) |
| 4Z8M | Crystal structure of the MAVS-TRAF6 complex | x-ray diffraction | C, D | — | 2 (best 0.33) |
| 4Z8M | Crystal structure of the mavs-TRAF6 complex | x-ray diffraction | C, D | — | 2 (best 0.33) |
| 7DNI | MDA5 CARDs-MAVS CARD polyUb complex | electron microscopy | M, N, O, P | — | 9 (best 0.89) |
| 7DNI | MDA5 cards-mavs card polyub complex | electron microscopy | M, N, O, P | — | — |
| 8WKW | Structure of MAVS-CARD Filament | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z | — | 20 (best 0.86) |
| Q7Z434 | AlphaFold monomer V2.0 prediction for mitochondrial antiviral- signaling protein (Q7Z434) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3J6C chain A against the predicted model Q7Z434: TM-score 0.98, RMSD 0.79 Å
- 3J6C chain A against the predicted model Q7Z434: TM-score 0.98, RMSD 0.79 Å
- 7DNI chain O against the predicted model Q7Z434: TM-score 0.97, RMSD 0.89 Å
- 7DNI chain O against the predicted model Q7Z434: TM-score 0.97, RMSD 0.89 Å
- 7DNI chain M against the predicted model Q7Z434: TM-score 0.97, RMSD 0.88 Å
- 7DNI chain M against the predicted model Q7Z434: TM-score 0.97, RMSD 0.88 Å
- 7DNI chain N against the predicted model Q7Z434: TM-score 0.97, RMSD 0.91 Å
- 3J6J chain A against the predicted model Q7Z434: TM-score 0.97, RMSD 0.97 Å
- 3J6J chain A against the predicted model Q7Z434: TM-score 0.97, RMSD 0.97 Å
- 7DNI chain P against the predicted model Q7Z434: TM-score 0.96, RMSD 0.94 Å
Elsewhere
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