UniProt Q7TN37
Transient receptor potential cation channel subfamily M member 4 (Q7TN37)
Transient receptor potential cation channel subfamily M member 4 (UniProt Q7TN37): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q7TN37
- Protein
- Transient receptor potential cation channel subfamily M member 4
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 1 record with a druggable one
Structures
6 records of Q7TN37 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BCJ | Cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 ångström resolution | electron microscopy | B, A, C, D | NA | — |
| 6BCL | cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 angstrom resolution | electron microscopy | B, A, C, D | NA | — |
| 6BCL | Cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 ångström resolution | electron microscopy | B, A, C, D | NA | — |
| 6BCO | Cryo-EM structure of TRPM4 in ATP bound state with short coiled coil at 2.9 ångström resolution | electron microscopy | B, A, C, D | ATP | — |
| 6BCQ | Cryo-EM structure of TRPM4 in ATP bound state with long coiled coil at 3.3 ångström resolution | electron microscopy | B, A, C, D | ATP | — |
| Q7TN37 | AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M… | predicted | A | — | 16 (best 0.78) |
Ligands
Experiment against prediction
- 6BCJ chain B against the predicted model Q7TN37: TM-score 0.93, RMSD 2.87 Å
- 6BCL chain B against the predicted model Q7TN37: TM-score 0.93, RMSD 3.06 Å
- 6BCL chain B against the predicted model Q7TN37: TM-score 0.93, RMSD 3.06 Å
- 6BCO chain B against the predicted model Q7TN37: TM-score 0.90, RMSD 3.45 Å
- 6BCQ chain B against the predicted model Q7TN37: TM-score 0.90, RMSD 3.57 Å
Elsewhere
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