UniProt Q7LDG7
RAS guanyl-releasing protein 2 (Q7LDG7)
RAS guanyl-releasing protein 2 (UniProt Q7LDG7): 4 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7LDG7
- Protein
- RAS guanyl-releasing protein 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of Q7LDG7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MA2 | Solution structure of RasGRP2 EF hands bound to calcium | solution nmr | A | — | — |
| 2MA2 | Solution structure of RASGRP2 ef hands bound to calcium | solution nmr | A | — | — |
| 6AXF | Structure of RasGRP2 in complex with Rap1B | x-ray diffraction | A, C, E, G, I, K, M, O | — | 20 (best 0.83) |
| 6AXF | Structure of RASGRP2 in complex with RAP1B | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| Q7LDG7 | AlphaFold monomer V2.0 prediction for RAS guanyl-releasing protein 2 (Q7LDG7) | predicted | A | — | — |
Experiment against prediction
- 6AXF chain K against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.12 Å
- 6AXF chain K against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.12 Å
- 6AXF chain I against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.13 Å
- 6AXF chain I against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.13 Å
- 6AXF chain O against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.24 Å
- 6AXF chain O against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.24 Å
- 6AXF chain M against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.16 Å
- 6AXF chain M against the predicted model Q7LDG7: TM-score 0.98, RMSD 1.16 Å
- 6AXF chain E against the predicted model Q7LDG7: TM-score 0.96, RMSD 1.36 Å
- 6AXF chain C against the predicted model Q7LDG7: TM-score 0.96, RMSD 1.44 Å
Elsewhere
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