UniProt Q7L8A9
Tubulinyl-Tyr carboxypeptidase 1 (Q7L8A9)
Tubulinyl-Tyr carboxypeptidase 1 (UniProt Q7L8A9), EC 3.4.17.17: 28 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q7L8A9
- Protein
- Tubulinyl-Tyr carboxypeptidase 1
- EC
- 3.4.17.17
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 53 · 9 records with a druggable one
Structures
29 records of Q7L8A9 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J4U | Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional… | x-ray diffraction | A | — | 2 (best 0.44) |
| 6J4U | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A | — | — |
| 6J7B | Crystal structure of VASH1-SVBP in complex with epoY | x-ray diffraction | A | BJL | 3 (best 0.67) |
| 6J7B | Crystal structure of VASH1-svbp in complex with epoy | x-ray diffraction | A | BJL | — |
| 6J8F | Crystal structure of SVBP-VASH1 with peptide mimic the C-terminal of alpha-tubulin | x-ray diffraction | B | — | 1 (best 0.51) |
| 6J8F | Crystal structure of svbp-VASH1 with peptide mimic the C-terminal of alpha-tubulin | x-ray diffraction | B | — | — |
| 6J8N | Crystal structure of SVBP-VASH1 complex, mutation C169A of VASH1 | x-ray diffraction | B, D | — | — |
| 6J8N | Crystal structure of svbp-VASH1 complex, mutation C169A of VASH1 | x-ray diffraction | B, D | — | — |
| 6J8O | Structure of a hypothetical protease | x-ray diffraction | B | — | 3 (best 0.54) |
| 6J8O | Structure of a hypothetical protease | x-ray diffraction | B | — | — |
| 6J91 | Structure of a hypothetical protease | x-ray diffraction | B | — | 2 (best 0.50) |
| 6J91 | Structure of a hypothetical protease | x-ray diffraction | B | — | — |
| 6J9H | Crystal structure of SVBP-VASH1 complex | x-ray diffraction | B, D | — | 7 (best 0.73) |
| 6J9H | Crystal structure of svbp-VASH1 complex | x-ray diffraction | B, D | — | — |
| 6K81 | Crystal structure of human VASH1-SVBP complex | x-ray diffraction | A | — | 4 (best 0.46) |
| 6K81 | Crystal structure of human VASH1-svbp complex | x-ray diffraction | A | — | — |
| 6LPG | human VASH1-SVBP complex | x-ray diffraction | A | SO4 | 4 (best 0.49) |
| 6LPG | Human VASH1-svbp complex | x-ray diffraction | A | SO4 | — |
| 6NVQ | Crystal structure of the VASH1-SVBP complex | x-ray diffraction | C | — | 3 (best 0.53) |
| 6NVQ | Crystal structure of the VASH1-svbp complex | x-ray diffraction | C | — | — |
| 6OCF | The crystal structure of VASH1-SVBP complex | x-ray diffraction | A | CL | 3 (best 0.43) |
| 6OCF | The crystal structure of VASH1-svbp complex | x-ray diffraction | A | — | — |
| 6OCG | Crystal structure of VASH1-SVBP complex bound with EpoY | x-ray diffraction | A | CL, BJL | 3 (best 0.54) |
| 6OCG | Crystal structure of VASH1-svbp complex bound with epoy | x-ray diffraction | A | CL, BJL | — |
| 6OCH | Crystal structure of VASH1-SVBP complex bound with parthenolide | x-ray diffraction | A, C | M4Y, SO4 | 6 (best 0.74) |
| 6OCH | Crystal structure of VASH1-svbp complex bound with parthenolide | x-ray diffraction | A, C | M4Y, SO4 | — |
| 6WSL | Cryo-EM structure of VASH1-SVBP bound to microtubules | electron microscopy | C, G | — | 8 (best 0.71) |
| 6WSL | Cryo-EM structure of VASH1-svbp bound to microtubules | electron microscopy | C, G | — | — |
| Q7L8A9 | AlphaFold monomer V2.0 prediction for tubulinyl-tyr carboxypeptidase 1 (Q7L8A9) | predicted | A | — | 4 (best 0.75) |
Ligands
Experiment against prediction
- 6NVQ chain C against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.46 Å
- 6NVQ chain C against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.46 Å
- 6K81 chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.49 Å
- 6K81 chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.49 Å
- 6OCH chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.48 Å
- 6OCH chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.48 Å
- 6OCH chain C against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.48 Å
- 6OCG chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.50 Å
- 6OCG chain A against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.50 Å
- 6J8O chain B against the predicted model Q7L8A9: TM-score 0.99, RMSD 0.56 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.