UniProt Q7L014

Probable ATP-dependent RNA helicase DDX46 (Q7L014)

Probable ATP-dependent RNA helicase DDX46 (UniProt Q7L014), EC 3.6.4.13: 8 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q7L014
Protein: Probable ATP-dependent RNA helicase DDX46
EC: 3.6.4.13
Experimental structures: 8
Predicted models: 1
Pockets: 5 · 2 records with a druggable one

Structures

9 records of Q7L014 in the MolNFT archive: 8 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6Y50	5'domain of human 17S U2 snRNP	electron microscopy	p	—	—
6Y50	5'DOMAIN of human 17S U2 snrnp	electron microscopy	p	—	—
6Y53	human 17S U2 snRNP low resolution part	electron microscopy	p	—	3 (best 0.70)
6Y53	Human 17S U2 snrnp low resolution part	electron microscopy	p	—	—
6Y5Q	Human 17S U2 snrnp	electron microscopy	p	—	—
7Q3L	Human 17S U2 snRNP 5' domain	electron microscopy	p	—	1 (best 0.40)
7Q3L	Human 17S U2 snrnp 5' domain	electron microscopy	p	—	—
7VPX	The cryo-EM structure of the human pre-A complex	electron microscopy	E	—	1 (best 0.71)
Q7L014	AlphaFold monomer V2.0 prediction for probable ATP-dependent RNA helicase DDX46 (Q7L014)	predicted	A	—	—

Experiment against prediction

6Y50 chain p against the predicted model Q7L014: TM-score 0.68, RMSD 1.79 Å
6Y50 chain p against the predicted model Q7L014: TM-score 0.68, RMSD 1.79 Å
7Q3L chain p against the predicted model Q7L014: TM-score 0.59, RMSD 0.72 Å
7Q3L chain p against the predicted model Q7L014: TM-score 0.59, RMSD 0.72 Å
6Y53 chain p against the predicted model Q7L014: TM-score 0.57, RMSD 2.11 Å
6Y53 chain p against the predicted model Q7L014: TM-score 0.57, RMSD 2.11 Å
6Y5Q chain p against the predicted model Q7L014: TM-score 0.51, RMSD 2.24 Å
7VPX chain E against the predicted model Q7L014: TM-score 0.50, RMSD 2.24 Å

Elsewhere

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