UniProt Q7A225
Endoribonuclease HigB (Q7A225)
Endoribonuclease HigB (UniProt Q7A225), EC 3.1.-.-: 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7A225
- Protein
- Endoribonuclease HigB
- EC
- 3.1.-.-
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
17 records of Q7A225 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MCT | P. vulgaris HIGBA structure, crystal form 1 | x-ray diffraction | B, D | — | — |
| 4MCT | P. vulgaris higba structure, crystal form 1 | x-ray diffraction | B, D | — | — |
| 4MCX | P. vulgaris HIGBA structure, crystal form 2 | x-ray diffraction | B, D, F | — | — |
| 4MCX | P. vulgaris higba structure, crystal form 2 | x-ray diffraction | B, D, F | — | — |
| 4PX8 | Structure of P. vulgaris HigB toxin | x-ray diffraction | A | — | — |
| 4PX8 | Structure of P. vulgaris higb toxin | x-ray diffraction | A | — | — |
| 4W4G | Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon | x-ray diffraction | QY, XY | — | — |
| 4YPB | Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon | x-ray diffraction | QY, XY | — | — |
| 4YY3 | 30S ribosomal subunit- HigB complex | x-ray diffraction | Y | — | — |
| 4YY3 | 30S ribosomal subunit- higb complex | x-ray diffraction | Y | — | — |
| 4YZV | Precleavage 70S structure of the P. vulgaris HigB deltaH92 toxin bound to the ACA codon | x-ray diffraction | QY, XY | — | — |
| 4ZSN | 70S-wild-type HigB toxin complex bound to a AAA lysine codon | x-ray diffraction | QY, XY | — | 1 (best 0.87) |
| 5IWH | Structure of P. vulgaris HigB toxin delta H92 | x-ray diffraction | A | CL | — |
| 5IWH | Structure of P. vulgaris higb toxin delta H92 | x-ray diffraction | A | — | — |
| 5IXL | Structure of P. vulgaris HigB toxin Y91A variant | x-ray diffraction | A, B, C, D, E, F, G, H | CL | 7 (best 0.82) |
| 5IXL | Structure of P. vulgaris higb toxin Y91A variant | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| Q7A225 | AlphaFold monomer V2.0 prediction for endoribonuclease higb (Q7A225) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 5IXL chain F against the predicted model Q7A225: TM-score 0.99, RMSD 0.34 Å
- 5IXL chain E against the predicted model Q7A225: TM-score 0.93, RMSD 0.36 Å
- 5IXL chain A against the predicted model Q7A225: TM-score 0.92, RMSD 0.38 Å
- 5IXL chain A against the predicted model Q7A225: TM-score 0.92, RMSD 0.38 Å
- 5IXL chain C against the predicted model Q7A225: TM-score 0.99, RMSD 0.38 Å
- 5IXL chain C against the predicted model Q7A225: TM-score 0.99, RMSD 0.38 Å
- 5IXL chain D against the predicted model Q7A225: TM-score 0.97, RMSD 0.40 Å
- 5IXL chain D against the predicted model Q7A225: TM-score 0.97, RMSD 0.40 Å
- 4YZV chain XY against the predicted model Q7A225: TM-score 0.99, RMSD 0.39 Å
- 4YZV chain QY against the predicted model Q7A225: TM-score 0.99, RMSD 0.42 Å
Elsewhere
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