UniProt Q74DF6
Sir2 superfamily protein (Q74DF6)
Sir2 superfamily protein (UniProt Q74DF6): 4 experimental structures on GenesisL1, 2 ligands bound, 43 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q74DF6
- Protein
- Sir2 superfamily protein
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 43 · 4 records with a druggable one
Structures
4 records of Q74DF6 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8IN8 | Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex | electron microscopy | B | — | 7 (best 0.80) |
| 8JKZ | Cryo-EM structure of the prokaryotic SPARSA system complex | electron microscopy | A | NAD | 13 (best 0.82) |
| 8K88 | Structure of procaryotic Ago | electron microscopy | B | — | 6 (best 0.85) |
| 8Y82 | Cryo-EM structure of the tetrameric SPARSA gRNA-ssDNA-NAD+ complex | electron microscopy | A, E, I, M | AMP | 17 (best 0.86) |
Ligands
Elsewhere
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