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UniProt Q74DF5

Piwi domain protein (Q74DF5)

Piwi domain protein (UniProt Q74DF5): 5 experimental structures on GenesisL1, 2 ligands bound, 54 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q74DF5
Protein
Piwi domain protein
Experimental structures
5
Predicted models
0
Ligands
2
Pockets
54 · 5 records with a druggable one

Structures

5 records of Q74DF5 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8IN8Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complexelectron microscopyCMG10 (best 0.80)
8JKZCryo-EM structure of the prokaryotic SPARSA system complexelectron microscopyBNAD13 (best 0.82)
8K88Structure of procaryotic Agoelectron microscopyAMG8 (best 0.85)
8Y7ZCryo-EM structure of the monomeric SPARSA gRNA-ssDNA complexelectron microscopyBMG5 (best 0.86)
8Y82Cryo-EM structure of the tetrameric SPARSA gRNA-ssDNA-NAD+ complexelectron microscopyB, F, J, NMG18 (best 0.86)

Ligands

  • MG · Magnesium ion · in 4 records
  • NAD · Nicotinamide-adenine-dinucleotide · in 1 record

Elsewhere

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