UniProt Q72L77
50S ribosomal protein L35 (Q72L77)
50S ribosomal protein L35 (UniProt Q72L77): 23 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q72L77
- Protein
- 50S ribosomal protein L35
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 29 · 8 records with a druggable one
Structures
24 records of Q72L77 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V4I | Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements. | x-ray diffraction | a | — | — |
| 4V4J | Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome. | x-ray diffraction | a | — | — |
| 4V63 | Structural basis for translation termination on the 70S ribosome. | x-ray diffraction | B8, D8 | — | — |
| 4V67 | Crystal structure of a translation termination complex formed with release factor RF2. | x-ray diffraction | B8, D8 | — | — |
| 4V7P | Recognition of the amber stop codon by release factor RF1. | x-ray diffraction | B5, C5 | — | — |
| 4V83 | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S… | x-ray diffraction | B5, D5 | — | — |
| 4V84 | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | x-ray diffraction | B5, D5 | — | — |
| 4V9J | 70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B8, D8 | — | — |
| 4V9K | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B8, D8 | — | — |
| 4V9L | 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B8, D8 | — | — |
| 4V9M | 70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B8, D8 | — | — |
| 4V9N | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | x-ray diffraction | B8, D8 | — | — |
| 4V9Q | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | x-ray diffraction | A5, C5 | — | — |
| 4W29 | 70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA… | x-ray diffraction | B8, D8 | — | — |
| 4XEJ | IRES bound to bacterial Ribosome | x-ray diffraction | AL35, BL35 | — | 3 (best 0.88) |
| 4ZER | Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome | x-ray diffraction | 18, 28 | MG | 5 (best 0.89) |
| 5E81 | Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with wobble… | x-ray diffraction | Q8, M5 | MG | 3 (best 0.89) |
| 5J4D | E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon | x-ray diffraction | FA, KC | MG | 3 (best 0.86) |
| 5V8I | Thermus thermophilus 70S ribosome lacking ribosomal protein uS17 | x-ray diffraction | 18, 28 | MG | 4 (best 0.88) |
| 6B4V | Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome | x-ray diffraction | FA, JC | MG | 4 (best 0.89) |
| 6BOH | Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the… | x-ray diffraction | FA, KC | MG | 4 (best 0.87) |
| 6BOK | E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome | x-ray diffraction | FA, IC | MG | — |
| 6N1D | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric… | x-ray diffraction | AL35, BL35 | MG | 3 (best 0.88) |
| Q72L77 | AlphaFold monomer V2.0 prediction for 50S ribosomal protein L35 (Q72L77) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 8 records
Experiment against prediction
- 6BOK chain FA against the predicted model Q72L77: TM-score 0.95, RMSD 0.62 Å
- 5J4D chain FA against the predicted model Q72L77: TM-score 0.95, RMSD 0.63 Å
- 5J4D chain KC against the predicted model Q72L77: TM-score 0.95, RMSD 0.64 Å
- 4ZER chain 18 against the predicted model Q72L77: TM-score 0.95, RMSD 0.64 Å
- 5V8I chain 18 against the predicted model Q72L77: TM-score 0.95, RMSD 0.66 Å
- 4ZER chain 28 against the predicted model Q72L77: TM-score 0.95, RMSD 0.67 Å
- 6BOH chain FA against the predicted model Q72L77: TM-score 0.94, RMSD 0.69 Å
- 6BOH chain KC against the predicted model Q72L77: TM-score 0.94, RMSD 0.70 Å
- 5V8I chain 28 against the predicted model Q72L77: TM-score 0.94, RMSD 0.70 Å
- 6B4V chain FA against the predicted model Q72L77: TM-score 0.94, RMSD 0.79 Å
Elsewhere
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