UniProt Q72JU9
50S ribosomal protein L19 (Q72JU9)
50S ribosomal protein L19 (UniProt Q72JU9): 20 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q72JU9
- Protein
- 50S ribosomal protein L19
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 4 records with a druggable one
Structures
21 records of Q72JU9 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V4I | Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements. | x-ray diffraction | N | — | — |
| 4V4J | Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome. | x-ray diffraction | N | — | — |
| 4V63 | Structural basis for translation termination on the 70S ribosome. | x-ray diffraction | BT, DT | — | — |
| 4V67 | Crystal structure of a translation termination complex formed with release factor RF2. | x-ray diffraction | BT, DT | — | — |
| 4V7P | Recognition of the amber stop codon by release factor RF1. | x-ray diffraction | BP, CP | — | — |
| 4V83 | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S… | x-ray diffraction | BP, DP | — | — |
| 4V84 | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | x-ray diffraction | BP, DP | — | — |
| 4V9J | 70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | BT, DT | — | — |
| 4V9K | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | BT, DT | — | — |
| 4V9L | 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | BT, DT | — | — |
| 4V9M | 70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | BT, DT | — | — |
| 4V9N | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | x-ray diffraction | BT, DT | — | — |
| 4V9Q | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | x-ray diffraction | AP, CP | — | — |
| 4XEJ | IRES bound to bacterial Ribosome | x-ray diffraction | AL19, BL19 | — | — |
| 5J4D | E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon | x-ray diffraction | Q, VB | MG | 2 (best 0.87) |
| 5V8I | Thermus thermophilus 70S ribosome lacking ribosomal protein uS17 | x-ray diffraction | 1T, 2T | MG | — |
| 6B4V | Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome | x-ray diffraction | Q, UB | MG | 1 (best 0.88) |
| 6BOH | Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the… | x-ray diffraction | Q, VB | MG | 1 (best 0.87) |
| 6BOK | E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome | x-ray diffraction | Q, TB | MG | — |
| 6N1D | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric… | x-ray diffraction | AL19, BL19 | MG | 1 (best 0.88) |
| Q72JU9 | AlphaFold monomer V2.0 prediction for 50S ribosomal protein L19 (Q72JU9) | predicted | A | — | 1 (best 0.36) |
Ligands
- MG · Magnesium ion · in 6 records
Experiment against prediction
- 5V8I chain 1T against the predicted model Q72JU9: TM-score 0.99, RMSD 0.48 Å
- 5J4D chain Q against the predicted model Q72JU9: TM-score 0.98, RMSD 0.66 Å
- 6B4V chain Q against the predicted model Q72JU9: TM-score 0.98, RMSD 0.68 Å
- 6BOK chain Q against the predicted model Q72JU9: TM-score 0.98, RMSD 0.72 Å
- 6BOH chain Q against the predicted model Q72JU9: TM-score 0.97, RMSD 0.79 Å
- 4V84 chain BP against the predicted model Q72JU9: TM-score 0.96, RMSD 0.87 Å
- 4V9Q chain AP against the predicted model Q72JU9: TM-score 0.96, RMSD 0.87 Å
- 4V83 chain BP against the predicted model Q72JU9: TM-score 0.96, RMSD 0.89 Å
- 4V9N chain BT against the predicted model Q72JU9: TM-score 0.96, RMSD 0.93 Å
- 4V67 chain BT against the predicted model Q72JU9: TM-score 0.96, RMSD 0.93 Å
Elsewhere
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