UniProt Q72874
Protease (Q72874)
Protease (UniProt Q72874): 15 experimental structures on GenesisL1, 3 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q72874
- Protein
- Protease
- Experimental structures
- 15
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 5 · 3 records with a druggable one
Structures
15 records of Q72874 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FB7 | Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the… | x-ray diffraction | A | — | — |
| 1FB7 | Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the… | x-ray diffraction | A | — | — |
| 2NPH | Crystal structure of HIV1 protease in situ product complex | x-ray diffraction | A, B | — | — |
| 2NPH | Crystal structure of HIV1 protease in situ product complex | x-ray diffraction | A, B | — | — |
| 4QLH | Crystal structure of drug resistant V82S/V1082S HIV-1 Protease | x-ray diffraction | A | — | — |
| 4QLH | Crystal structure of drug resistant V82S/V1082S HIV-1 protease | x-ray diffraction | A | — | — |
| 5KAO | Crystal structure of wild type HIV-1 protease in complex with GRL-10413 | x-ray diffraction | A, B | G43 | 1 (best 0.71) |
| 5KAO | Crystal structure of wild type HIV-1 protease in complex with grl- 10413 | x-ray diffraction | A, B | G43 | — |
| 5V4Y | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-09510 | x-ray diffraction | A | 8FM | 2 (best 0.45) |
| 5V4Y | X-ray crystal structure of wild type HIV-1 protease in complex with grl-09510 | x-ray diffraction | A | 8FM | — |
| 7DOZ | HIV-1 Protease D30N mutant in complex with Nelfinavir | x-ray diffraction | A | 1UN | 1 (best 0.71) |
| 7DOZ | HIV-1 protease D30N mutant in complex with nelfinavir | x-ray diffraction | A | 1UN | — |
| 7DPQ | HIV-1 Protease D30N mutant | x-ray diffraction | A | — | 1 (best 0.72) |
| 7DPQ | HIV-1 protease D30N mutant | x-ray diffraction | A | — | — |
| 7DT9 | D30N HIV protease in complex with saquinavir | x-ray diffraction | A | — | — |
Ligands
- 1UN · 2-[2-hydroxy-3-(3-hydroxy-2-methyl-benzoylamino)-4-phenyl sulfanyl-butyl]-decahydro-isoquinoline-3-carboxylic acid tert-butylamide · in 2 records
- 8FM · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · in 2 records
- G43 · [(3~{A}~{S},4~{R},6~{A}~{R})-2,3,3~{A},4,5,6~{A}-hexahydrofuro[2,3-b]furan-4-yl] ~{N}-[(2~{S},3~{R})-1-(3-chloranyl-4-methoxy-phenyl)-4-[(4-methoxyphenyl) sulfonyl-(2-methylpropyl)amino]-3-oxidanyl-butan-2-yl]carbamate · in 2 records
Elsewhere
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