UniProt Q71RJ2
Voltage-dependent calcium channel gamma-2 subunit (Q71RJ2)
Voltage-dependent calcium channel gamma-2 subunit (UniProt Q71RJ2): 20 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 70 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q71RJ2
- Protein
- Voltage-dependent calcium channel gamma-2 subunit
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 70 · 13 records with a druggable one
Structures
21 records of Q71RJ2 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KK2 | Architecture of fully occupied GluA2 AMPA receptor - TARP complex elucidated by single particle… | electron microscopy | E, F, G, H | — | 8 (best 0.80) |
| 5KK2 | Architecture of fully occupied GLUA2 AMPA receptor - tarp complex elucidated by single particle… | electron microscopy | E, F, G, H | — | — |
| 5VOT | Structure of AMPA receptor-TARP complex | electron microscopy | E, F, G, H | — | 9 (best 0.84) |
| 5VOT | Structure of AMPA receptor-tarp complex | electron microscopy | E, F, G, H | — | — |
| 5VOU | Structure of AMPA receptor-TARP complex | electron microscopy | E, H, G, F | — | 7 (best 0.77) |
| 5VOU | Structure of AMPA receptor-tarp complex | electron microscopy | E, H, G, F | — | — |
| 5VOV | Structure of AMPA receptor-TARP complex | electron microscopy | E, F, G, H | — | 12 (best 0.80) |
| 5VOV | Structure of AMPA receptor-tarp complex | electron microscopy | E, F, G, H | — | — |
| 6NJL | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | 2 (best 0.81) |
| 6NJL | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | — |
| 6NJM | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | 2 (best 0.81) |
| 6NJM | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | — |
| 6NJN | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | 2 (best 0.79) |
| 6NJN | Architecture and subunit arrangement of native AMPA receptors | electron microscopy | F, H | — | — |
| 8C1R | Resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma-2 | electron microscopy | E, F, G, H | PLM, POV | 3 (best 0.62) |
| 8P3Q | Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized… | electron microscopy | E, F, G, H | POV, PLM | 5 (best 0.62) |
| 8P3X | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized… | electron microscopy | E, F, G, H | — | 5 (best 0.60) |
| 8P3Y | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized… | electron microscopy | E, F, G, H | — | 5 (best 0.61) |
| 8P3Z | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized… | electron microscopy | E, F, G, H | — | 5 (best 0.61) |
| 8PIV | Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized… | electron microscopy | E, F, G, H | PLM, POV | 5 (best 0.60) |
| Q71RJ2 | AlphaFold monomer V2.0 prediction for voltage-dependent calcium channel gamma-2 subunit (Q71RJ2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8PIV chain G against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.86 Å
- 8P3Y chain G against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.87 Å
- 8C1R chain G against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.85 Å
- 8P3X chain G against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.86 Å
- 8P3Z chain E against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.88 Å
- 8C1R chain E against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.88 Å
- 8P3Q chain G against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.88 Å
- 8P3Y chain F against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.89 Å
- 8PIV chain F against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.89 Å
- 8P3Y chain E against the predicted model Q71RJ2: TM-score 0.97, RMSD 0.90 Å
Elsewhere
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