UniProt Q70Z35
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (Q70Z35)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (UniProt Q70Z35): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment…
- UniProt
- Q70Z35
- Protein
- Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of Q70Z35 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BNM | Crystal Structure of the P-Rex2 PH domain | x-ray diffraction | A | CL | — |
| 6BNM | Crystal structure of the P-REX2 pH domain | x-ray diffraction | A | CL | — |
| Q70Z35 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate-dependent rac… | predicted | A | — | 20 (best 0.85) |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 6BNM chain A against the predicted model Q70Z35: TM-score 0.96, RMSD 1.31 Å
- 6BNM chain A against the predicted model Q70Z35: TM-score 0.96, RMSD 1.31 Å
Elsewhere
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