UniProt Q6ZMT1
SH3 and cysteine-rich domain-containing protein 2 (Q6ZMT1)
SH3 and cysteine-rich domain-containing protein 2 (UniProt Q6ZMT1): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6ZMT1
- Protein
- SH3 and cysteine-rich domain-containing protein 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 2 records with a druggable one
Structures
7 records of Q6ZMT1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6B26 | Crystal structure of human STAC2 Tandem SH3 Domains (296-411) | x-ray diffraction | A | — | — |
| 6B26 | Crystal structure of human STAC2 tandem SH3 domains (296-411) | x-ray diffraction | A | — | — |
| 6B27 | Crystal structure of human STAC2 Tandem SH3 Domains (296-411) in complex with a CaV1.1 II-III loop… | x-ray diffraction | A, B, C, D, E, F | SO4, CL | 11 (best 0.61) |
| 6B27 | Crystal structure of human STAC2 tandem SH3 domains (296-411) in complex with a CAV1.1 II-III loop… | x-ray diffraction | A, B, C, D, E, F | SO4, CL | — |
| 6B28 | Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411) | x-ray diffraction | A | — | — |
| 6B28 | Crystal structure of human STAC2 tandem SH3 domains Q347I (296-411) | x-ray diffraction | A | — | — |
| Q6ZMT1 | AlphaFold monomer V2.0 prediction for SH3 and cysteine-rich domain- containing protein 2 (Q6ZMT1) | predicted | A | — | 1 (best 0.60) |
Ligands
Experiment against prediction
- 6B27 chain B against the predicted model Q6ZMT1: TM-score 0.97, RMSD 0.79 Å
- 6B27 chain B against the predicted model Q6ZMT1: TM-score 0.97, RMSD 0.79 Å
- 6B27 chain E against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.80 Å
- 6B27 chain E against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.80 Å
- 6B28 chain A against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.81 Å
- 6B28 chain A against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.81 Å
- 6B27 chain C against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.86 Å
- 6B27 chain C against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.86 Å
- 6B27 chain D against the predicted model Q6ZMT1: TM-score 0.96, RMSD 0.88 Å
- 6B27 chain A against the predicted model Q6ZMT1: TM-score 0.96, RMSD 1.03 Å
Elsewhere
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