UniProt Q6ZMJ4
Interleukin-34 (Q6ZMJ4)
Interleukin-34 (UniProt Q6ZMJ4): 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6ZMJ4
- Protein
- Interleukin-34
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
9 records of Q6ZMJ4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DKC | Crystal Structure of Human Interleukin-34 | x-ray diffraction | A, B | — | — |
| 4DKC | Crystal structure of human interleukin-34 | x-ray diffraction | A, B | — | — |
| 4DKD | Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R | x-ray diffraction | A, B | — | — |
| 4DKD | Crystal structure of human interleukin-34 bound to human csf-1R | x-ray diffraction | A, B | — | — |
| 4DKE | Crystal Structure of Human Interleukin-34 Bound to FAb1.1 | x-ray diffraction | A, B | — | — |
| 4DKE | Crystal structure of human interleukin-34 bound to FAB1.1 | x-ray diffraction | A, B | — | — |
| 4DKF | Crystal Structure of Human Interleukin-34 Bound to FAb2 | x-ray diffraction | A, B | — | — |
| 4DKF | Crystal structure of human interleukin-34 bound to FAB2 | x-ray diffraction | A, B | — | — |
| Q6ZMJ4 | AlphaFold monomer V2.0 prediction for interleukin-34 (Q6ZMJ4) | predicted | A | — | 1 (best 0.62) |
Experiment against prediction
- 4DKC chain A against the predicted model Q6ZMJ4: TM-score 0.99, RMSD 0.52 Å
- 4DKC chain A against the predicted model Q6ZMJ4: TM-score 0.99, RMSD 0.52 Å
- 4DKC chain B against the predicted model Q6ZMJ4: TM-score 0.99, RMSD 0.54 Å
- 4DKC chain B against the predicted model Q6ZMJ4: TM-score 0.99, RMSD 0.54 Å
- 4DKE chain A against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.60 Å
- 4DKE chain A against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.60 Å
- 4DKF chain A against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.68 Å
- 4DKF chain A against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.68 Å
- 4DKD chain B against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.71 Å
- 4DKD chain B against the predicted model Q6ZMJ4: TM-score 0.98, RMSD 0.71 Å
Elsewhere
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