UniProt Q6WG30
Taxadiene 5-alpha hydroxylase (Q6WG30)
Taxadiene 5-alpha hydroxylase (UniProt Q6WG30), EC 1.14.14.176: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q6WG30
- Protein
- Taxadiene 5-alpha hydroxylase
- EC
- 1.14.14.176
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 11 · 3 records with a druggable one
Structures
3 records of Q6WG30 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8X1W | CYP725A4 apo structure | x-ray diffraction | A | HEM | 4 (best 0.86) |
| 8X3E | CYP725A4-Taxa-4,11-diene complex | x-ray diffraction | A | A1L3H, HEM | 3 (best 0.85) |
| Q6WG30 | AlphaFold monomer V2.0 prediction for taxadiene 5-alpha hydroxylase (Q6WG30) | predicted | A | — | 4 (best 0.85) |
Ligands
Experiment against prediction
- 8X3E chain A against the predicted model Q6WG30: TM-score 0.99, RMSD 0.80 Å
- 8X1W chain A against the predicted model Q6WG30: TM-score 0.99, RMSD 0.85 Å
Elsewhere
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