UniProt Q6W0C5

Developmental pluripotency-associated protein 3 (Q6W0C5)

Developmental pluripotency-associated protein 3 (UniProt Q6W0C5): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt: Q6W0C5
Protein: Developmental pluripotency-associated protein 3
Experimental structures: 3
Predicted models: 1
Ligands: 1
Pockets: 15 · 2 records with a druggable one

Structures

4 records of Q6W0C5 in the MolNFT archive: 3 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8WMS	Crystal structure of human DPPA3 in complex with human UHRF1 PHD domain	x-ray diffraction	B	—	1 (best 0.31)
8XV7	Crystal structure of TTD-PHD domain of UHRF1 in complex with hStella peptide (residues 75-121)	x-ray diffraction	B, D, F, H	ZN	12 (best 0.82)
8XV8	Crystal structure of PHD domain of UHRF1 in complex with hStella peptide (residues 75-121)	x-ray diffraction	B, D, F, H	—	2 (best 0.67)
Q6W0C5	AlphaFold monomer V2.0 prediction for developmental pluripotency- associated protein 3 (Q6W0C5)	predicted	A	—	—

Ligands

ZN · Zinc ion · in 1 record

Experiment against prediction

8XV7 chain H against the predicted model Q6W0C5: TM-score 0.75, RMSD 1.44 Å
8XV8 chain F against the predicted model Q6W0C5: TM-score 0.66, RMSD 1.49 Å
8XV8 chain D against the predicted model Q6W0C5: TM-score 0.66, RMSD 2.18 Å
8XV8 chain B against the predicted model Q6W0C5: TM-score 0.65, RMSD 2.36 Å
8WMS chain B against the predicted model Q6W0C5: TM-score 0.65, RMSD 2.23 Å
8XV8 chain H against the predicted model Q6W0C5: TM-score 0.62, RMSD 1.89 Å
8XV7 chain D against the predicted model Q6W0C5: TM-score 0.60, RMSD 1.24 Å
8XV7 chain F against the predicted model Q6W0C5: TM-score 0.59, RMSD 1.71 Å
8XV7 chain B against the predicted model Q6W0C5: TM-score 0.58, RMSD 1.88 Å

Elsewhere

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