UniProt Q6UXV0
GDNF family receptor alpha-like (Q6UXV0)
GDNF family receptor alpha-like (UniProt Q6UXV0): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6UXV0
- Protein
- GDNF family receptor alpha-like
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
6 records of Q6UXV0 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VZ4 | Receptor-growth factor crystal structure at 2.20 Angstrom resolution | x-ray diffraction | B | SO4 | 3 (best 0.66) |
| 5VZ4 | Receptor-growth factor crystal structure at 2.20 ångström resolution | x-ray diffraction | B | SO4 | — |
| 6Q2J | Cryo-EM structure of extracellular dimeric complex of RET/GFRAL/GDF15 | electron microscopy | C, D | — | — |
| 6WMW | GFRAL receptor bound with two antibody Fabs (3P10, 25M22) | x-ray diffraction | B | — | 6 (best 0.71) |
| 6WMW | Gfral receptor bound with two antibody fabs (3P10, 25M22) | x-ray diffraction | B | — | — |
| Q6UXV0 | AlphaFold monomer V2.0 prediction for gdnf family receptor alpha-like (Q6UXV0) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6WMW chain B against the predicted model Q6UXV0: TM-score 0.99, RMSD 0.63 Å
- 6WMW chain B against the predicted model Q6UXV0: TM-score 0.99, RMSD 0.63 Å
- 5VZ4 chain B against the predicted model Q6UXV0: TM-score 0.98, RMSD 0.77 Å
- 5VZ4 chain B against the predicted model Q6UXV0: TM-score 0.98, RMSD 0.77 Å
- 6Q2J chain C against the predicted model Q6UXV0: TM-score 0.98, RMSD 0.74 Å
- 6Q2J chain D against the predicted model Q6UXV0: TM-score 0.98, RMSD 0.74 Å
Elsewhere
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