UniProt Q6Q899
Probable ATP-dependent RNA helicase DDX58 (Q6Q899)
Probable ATP-dependent RNA helicase DDX58 (UniProt Q6Q899), EC 3.6.4.13: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6Q899
- Protein
- Probable ATP-dependent RNA helicase DDX58
- EC
- 3.6.4.13
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
5 records of Q6Q899 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3TBK | Mouse RIG-I ATPase Domain | x-ray diffraction | A | — | — |
| 3TBK | Mouse rig-I ATPase domain | x-ray diffraction | A | — | — |
| 6BZH | Structure of mouse RIG-I tandem CARDs | x-ray diffraction | A, B, C, D, E | CL | 9 (best 0.87) |
| 6BZH | Structure of mouse rig-I tandem cards | x-ray diffraction | A, B, C, D, E | CL | — |
| Q6Q899 | AlphaFold monomer V2.0 prediction for antiviral innate immune response receptor rig-I (Q6Q899) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 6BZH chain D against the predicted model Q6Q899: TM-score 0.97, RMSD 1.02 Å
- 6BZH chain D against the predicted model Q6Q899: TM-score 0.97, RMSD 1.02 Å
- 6BZH chain E against the predicted model Q6Q899: TM-score 0.96, RMSD 0.89 Å
- 6BZH chain E against the predicted model Q6Q899: TM-score 0.96, RMSD 0.89 Å
- 6BZH chain A against the predicted model Q6Q899: TM-score 0.95, RMSD 1.07 Å
- 6BZH chain A against the predicted model Q6Q899: TM-score 0.95, RMSD 1.07 Å
- 6BZH chain C against the predicted model Q6Q899: TM-score 0.95, RMSD 1.18 Å
- 6BZH chain C against the predicted model Q6Q899: TM-score 0.95, RMSD 1.18 Å
- 6BZH chain B against the predicted model Q6Q899: TM-score 0.94, RMSD 1.11 Å
- 6BZH chain B against the predicted model Q6Q899: TM-score 0.94, RMSD 1.11 Å
Elsewhere
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