UniProt Q6Q783
Histone-lysine N-methyltransferase SUV420H2 (Q6Q783)
Histone-lysine N-methyltransferase SUV420H2 (UniProt Q6Q783), EC 2.1.1.43: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6Q783
- Protein
- Histone-lysine N-methyltransferase SUV420H2
- EC
- 2.1.1.43
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 1 record with a druggable one
Structures
3 records of Q6Q783 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4AU7 | The structure of the Suv4-20h2 ternary complex with histone H4 | x-ray diffraction | A, B | SAH, ZN | 7 (best 0.65) |
| 4AU7 | The structure of the SUV4-20H2 ternary complex with histone H4 | x-ray diffraction | A, B | — | — |
| Q6Q783 | AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase KMT5C (Q6Q783) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4AU7 chain B against the predicted model Q6Q783: TM-score 0.98, RMSD 0.79 Å
- 4AU7 chain B against the predicted model Q6Q783: TM-score 0.98, RMSD 0.79 Å
- 4AU7 chain A against the predicted model Q6Q783: TM-score 0.98, RMSD 1.14 Å
- 4AU7 chain A against the predicted model Q6Q783: TM-score 0.97, RMSD 1.14 Å
Elsewhere
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