UniProt Q6PJF5
Inactive rhomboid protein 2 (Q6PJF5)
Inactive rhomboid protein 2 (UniProt Q6PJF5): 4 experimental structures and 1 predicted model on GenesisL1, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PJF5
- Protein
- Inactive rhomboid protein 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 42 · 5 records with a druggable one
Structures
5 records of Q6PJF5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8SNL | Structure of human ADAM17/iRhom2 sheddase complex | electron microscopy | B | — | 9 (best 0.77) |
| 8SNM | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain | electron microscopy | C | — | 10 (best 0.79) |
| 8SNN | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1 | electron microscopy | B | — | 11 (best 0.75) |
| 8SNO | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2 | electron microscopy | B | — | 8 (best 0.77) |
| Q6PJF5 | AlphaFold monomer V2.0 prediction for inactive rhomboid protein 2 (Q6PJF5) | predicted | A | — | 4 (best 0.79) |
Experiment against prediction
- 8SNM chain C against the predicted model Q6PJF5: TM-score 0.97, RMSD 1.55 Å
- 8SNL chain B against the predicted model Q6PJF5: TM-score 0.97, RMSD 1.55 Å
- 8SNN chain B against the predicted model Q6PJF5: TM-score 0.97, RMSD 1.55 Å
- 8SNO chain B against the predicted model Q6PJF5: TM-score 0.97, RMSD 1.58 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.