UniProt Q6PGP7
Tetratricopeptide repeat protein 37 (Q6PGP7)
Tetratricopeptide repeat protein 37 (UniProt Q6PGP7): 11 experimental structures and 1 predicted model on GenesisL1, 118 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PGP7
- Protein
- Tetratricopeptide repeat protein 37
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 118 · 8 records with a druggable one
Structures
12 records of Q6PGP7 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7QDR | Apo human SKI complex in the closed state | electron microscopy | B | — | 16 (best 0.82) |
| 7QDR | Apo human ski complex in the closed state | electron microscopy | B | — | — |
| 7QDS | Apo human SKI complex in the open state | electron microscopy | B | — | 20 (best 0.83) |
| 7QDS | Apo human ski complex in the open state | electron microscopy | B | — | — |
| 7QDY | RNA-bound human SKI complex | electron microscopy | B | — | 16 (best 0.83) |
| 7QDY | RNA-bound human ski complex | electron microscopy | B | — | — |
| 7QDZ | 80S-bound human SKI complex in the closed state | electron microscopy | B | — | 15 (best 0.83) |
| 7QDZ | 80S-bound human ski complex in the closed state | electron microscopy | B | — | — |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | B | — | 1 (best 0.83) |
| 9G8Q | 40S-bound human SKI238 complex in the open state (Gatekeeping module) | electron microscopy | B | — | 20 (best 0.82) |
| 9G8R | human SKI7-SKI238 complex in the open state | electron microscopy | B | — | 19 (best 0.82) |
| Q6PGP7 | AlphaFold monomer V2.0 prediction for tetratricopeptide repeat protein 37 (Q6PGP7) | predicted | A | — | 11 (best 0.69) |
Experiment against prediction
- 7QDZ chain B against the predicted model Q6PGP7: TM-score 0.90, RMSD 3.83 Å
- 7QDZ chain B against the predicted model Q6PGP7: TM-score 0.90, RMSD 3.83 Å
- 7QDS chain B against the predicted model Q6PGP7: TM-score 0.89, RMSD 3.76 Å
- 7QDS chain B against the predicted model Q6PGP7: TM-score 0.89, RMSD 3.76 Å
- 7QDY chain B against the predicted model Q6PGP7: TM-score 0.88, RMSD 4.44 Å
- 7QDY chain B against the predicted model Q6PGP7: TM-score 0.88, RMSD 4.44 Å
- 9G8O chain B against the predicted model Q6PGP7: TM-score 0.87, RMSD 3.87 Å
- 9G8Q chain B against the predicted model Q6PGP7: TM-score 0.87, RMSD 3.92 Å
- 7QDR chain B against the predicted model Q6PGP7: TM-score 0.87, RMSD 4.48 Å
- 7QDR chain B against the predicted model Q6PGP7: TM-score 0.87, RMSD 4.48 Å
Elsewhere
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