UniProt Q6PGF3
Mediator of RNA polymerase II transcription subunit 16 (Q6PGF3)
Mediator of RNA polymerase II transcription subunit 16 (UniProt Q6PGF3): 4 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PGF3
- Protein
- Mediator of RNA polymerase II transcription subunit 16
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 30 · 4 records with a druggable one
Structures
5 records of Q6PGF3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | K | — | 7 (best 0.87) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | K | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | K | — | 6 (best 0.87) |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | K | — | 3 (best 0.89) |
| Q6PGF3 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 16… | predicted | A | — | 14 (best 0.84) |
Experiment against prediction
- 6W1S chain K against the predicted model Q6PGF3: TM-score 0.94, RMSD 2.59 Å
- 6W1S chain K against the predicted model Q6PGF3: TM-score 0.94, RMSD 2.59 Å
- 8T1I chain K against the predicted model Q6PGF3: TM-score 0.92, RMSD 2.87 Å
- 8T1L chain K against the predicted model Q6PGF3: TM-score 0.92, RMSD 3.05 Å
Elsewhere
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