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UniProt Q6P9R4

Rho guanine nucleotide exchange factor 18 (Q6P9R4)

Rho guanine nucleotide exchange factor 18 (UniProt Q6P9R4): 2 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q6P9R4
Protein
Rho guanine nucleotide exchange factor 18
Experimental structures
2
Predicted models
1
Pockets
2 · 1 record with a druggable one

Structures

3 records of Q6P9R4 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6BCBA Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analogx-ray diffractionA—2 (best 0.52)
6BCBA complex between pH domain of P114RHOGEF and activated rhoa bound to a GTP analogx-ray diffractionA——
Q6P9R4AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 18 (Q6P9R4)predictedA——

Experiment against prediction

Elsewhere

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