UniProt Q6P549
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 (Q6P549)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 (UniProt Q6P549), EC 2.7.10.1, 3.1.3.86: 3 experimental structures on GenesisL1, 2 pockets. Binding sites, pockets, druggability and 3D structures…
- UniProt
- Q6P549
- Protein
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor…
- EC
- 2.7.10.1, 3.1.3.86
- Experimental structures
- 3
- Predicted models
- 0
- Pockets
- 2 · 1 record with a druggable one
Structures
3 records of Q6P549 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZRX | Crystal Structure of EphA2/SHIP2 Complex | x-ray diffraction | A, B | — | 2 (best 0.51) |
| 5ZRX | Crystal structure of EPHA2/SHIP2 complex | x-ray diffraction | A, B | — | — |
| Q6P549 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2… | — | — | — |
Experiment against prediction
- 5ZRX chain A against the predicted model Q03145: TM-score 0.64, RMSD 4.15 Å
- 5ZRX chain A against the predicted model Q03145: TM-score 0.64, RMSD 4.15 Å
- 5ZRX chain B against the predicted model Q03145: TM-score 0.64, RMSD 4.10 Å
- 5ZRX chain B against the predicted model Q03145: TM-score 0.64, RMSD 4.10 Å
Elsewhere
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