UniProt Q6P2C8
Mediator of RNA polymerase II transcription subunit 27 (Q6P2C8)
Mediator of RNA polymerase II transcription subunit 27 (UniProt Q6P2C8): 10 experimental structures on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6P2C8
- Protein
- Mediator of RNA polymerase II transcription subunit 27
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 9 · 3 records with a druggable one
Structures
10 records of Q6P2C8 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EMF | Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | electron microscopy | 0 | ZN | 6 (best 0.80) |
| 7EMF | Human mediator (deletion of MED1-idr) in a tail-extended conformation | electron microscopy | 0 | ZN | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | c | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | c | — | — |
| 7ENJ | Human mediator (deletion of MED1-idr) in a tail-bent conformation (med-B) | electron microscopy | 0 | ZN | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | p | ZN | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | p | ZN | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | c | ZN | 1 (best 0.81) |
| 8TQW | Structure of human transcriptional Mediator complex | electron microscopy | 0 | ZN | 2 (best 0.88) |
| Q6P2C8 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 27… | — | — | — |
Ligands
- ZN · Zinc ion · in 7 records
Elsewhere
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