UniProt Q6P1M3
LLGL scribble cell polarity complex component 2 (Q6P1M3)
LLGL scribble cell polarity complex component 2 (UniProt Q6P1M3): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q6P1M3
- Protein
- LLGL scribble cell polarity complex component 2
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
14 records of Q6P1M3 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WP0 | Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide | x-ray diffraction | B | — | — |
| 3WP0 | Crystal structure of dlg gk in complex with a phosphor-LGL2 peptide | x-ray diffraction | B | — | — |
| 3WP1 | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl | x-ray diffraction | A | — | — |
| 3WP1 | Phosphorylation-dependent interaction between tumor suppressors dlg and lgl | x-ray diffraction | A | — | — |
| 6N8P | Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2).… | x-ray diffraction | A | CL | — |
| 6N8P | Crystal structure of the human cell polarity protein lethal giant larvae 2 (LGL2).… | x-ray diffraction | A | CL | — |
| 6N8Q | Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2).… | x-ray diffraction | A | CL | — |
| 6N8Q | Crystal structure of the human cell polarity protein lethal giant larvae 2 (LGL2).… | x-ray diffraction | A | CL | — |
| 6N8R | Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC… | x-ray diffraction | A | CL | — |
| 6N8R | Crystal structure of the human cell polarity protein lethal giant larvae 2 (LGL2). apkc… | x-ray diffraction | A | CL | — |
| 6N8S | Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC… | x-ray diffraction | A, D | — | — |
| 6N8S | Crystal structure of the human cell polarity protein lethal giant larvae 2 (LGL2). apkc… | x-ray diffraction | A, D | — | — |
| 8R3X | Crystal structure of aPKC Iota kinase domain with LLGL2 peptide | x-ray diffraction | C, D | — | 4 (best 0.80) |
| Q6P1M3 | AlphaFold monomer V2.0 prediction for llgl scribble cell polarity complex component 2 (Q6P1M3) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 6 records
Experiment against prediction
- 6N8R chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.49 Å
- 6N8R chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.49 Å
- 6N8S chain D against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.48 Å
- 6N8S chain D against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.48 Å
- 6N8Q chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.56 Å
- 6N8Q chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.56 Å
- 6N8S chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.60 Å
- 6N8S chain A against the predicted model Q6P1M3: TM-score 1.00, RMSD 0.60 Å
- 6N8P chain A against the predicted model Q6P1M3: TM-score 0.99, RMSD 0.80 Å
- 6N8P chain A against the predicted model Q6P1M3: TM-score 0.99, RMSD 0.80 Å
Elsewhere
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