UniProt Q6P1K2
Polyamine-modulated factor 1 (Q6P1K2)
Polyamine-modulated factor 1 (UniProt Q6P1K2): 6 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6P1K2
- Protein
- Polyamine-modulated factor 1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 22 · 4 records with a druggable one
Structures
7 records of Q6P1K2 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LSJ | CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX | x-ray diffraction | B, E | — | 9 (best 0.75) |
| 5LSJ | Crystal structure of the human kinetochore MIS12-cenp-C delta-HEAD2 complex | x-ray diffraction | B, E | — | — |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | B | — | 1 (best 0.67) |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | B | — | — |
| 8PPR | Structure of the human outer kinetochore KMN network complex | electron microscopy | P | — | 4 (best 0.72) |
| 8Q5H | Human KMN network (outer kinetochore) | electron microscopy | B | — | 8 (best 0.85) |
| Q6P1K2 | AlphaFold monomer V2.0 prediction for polyamine-modulated factor 1 (Q6P1K2) | predicted | A | — | — |
Experiment against prediction
- 5LSK chain B against the predicted model Q6P1K2: TM-score 0.91, RMSD 1.65 Å
- 5LSK chain B against the predicted model Q6P1K2: TM-score 0.91, RMSD 1.65 Å
- 8PPR chain P against the predicted model Q6P1K2: TM-score 0.87, RMSD 2.25 Å
- 8Q5H chain B against the predicted model Q6P1K2: TM-score 0.87, RMSD 2.12 Å
- 5LSJ chain B against the predicted model Q6P1K2: TM-score 0.86, RMSD 2.48 Å
- 5LSJ chain B against the predicted model Q6P1K2: TM-score 0.86, RMSD 2.48 Å
Elsewhere
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