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UniProt Q6L5H6

Protein phosphatase 2C 50 (Q6L5H6)

Protein phosphatase 2C 50 (UniProt Q6L5H6): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q6L5H6
Protein
Protein phosphatase 2C 50
Experimental structures
7
Predicted models
1
Ligands
2
Pockets
4 · 1 record with a druggable one

Structures

8 records of Q6L5H6 in the MolNFT archive: 7 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5GWOCrystal structure of RCAR3:PP2C S265F/I267M with (+)-abax-ray diffractionA, B——
5GWPCrystal structure of RCAR3:PP2C wild-type with (+)-abax-ray diffractionA, B——
5ZCGCrystal structure of OSPP2C50 S265L/I267V:OSPYL/RCAR3 with (+)-abax-ray diffractionA, BMG—
5ZCHCrystal structure of OSPP2C50 I267W:OSPYL/RCAR3 with (+)-abax-ray diffractionA, BMG—
5ZCLCrystal structure of OSPP2C50 I267L:OSPYL/RCAR3 with (+)-abax-ray diffractionA, BMG—
5ZCUCrystal structure of RCAR3:PP2C wild-type with pyrabactinx-ray diffractionA, BMG, SO4—
5ZCUCrystal structure of RCAR3:PP2C wild-type with pyrabactinx-ray diffractionA, BMG, SO4—
Q6L5H6AlphaFold monomer V2.0 prediction for protein phosphatase 2C 50 (Q6L5H6)predictedA—4 (best 0.68)

Ligands

  • MG · Magnesium ion · in 5 records
  • SO4 · Sulfate ion · in 2 records

Experiment against prediction

Elsewhere

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