UniProt Q6JXI5
Telomerase-associated protein of 45 kDa (Q6JXI5)
Telomerase-associated protein of 45 kDa (UniProt Q6JXI5): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6JXI5
- Protein
- Telomerase-associated protein of 45 kDa
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
9 records of Q6JXI5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DOI | Crystal structure of Tetrahymena p45N and p19 | x-ray diffraction | E, F, G, H | — | — |
| 5DOI | Crystal structure of tetrahymena P45N and P19 | x-ray diffraction | E, F, G, H | — | — |
| 5DOK | Crystal structure of Tetrahymena p45C | x-ray diffraction | A, B | MG | — |
| 5DOK | Crystal structure of tetrahymena P45C | x-ray diffraction | A, B | — | — |
| 7UY5 | Tetrahymena telomerase with CST | electron microscopy | J | — | 1 (best 0.69) |
| 7UY5 | Tetrahymena telomerase with cst | electron microscopy | J | — | — |
| 7UY7 | Tetrahymena CST with Polymerase alpha-Primase | electron microscopy | B | — | 5 (best 0.80) |
| 7UY7 | Tetrahymena cst with polymerase alpha-primase | electron microscopy | B | — | — |
| Q6JXI5 | AlphaFold monomer V2.0 prediction for telomerase-associated protein of 45 kda (Q6JXI5) | predicted | A | — | 2 (best 0.43) |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 5DOK chain B against the predicted model Q6JXI5: TM-score 0.99, RMSD 0.55 Å
- 5DOK chain B against the predicted model Q6JXI5: TM-score 0.99, RMSD 0.55 Å
- 5DOK chain A against the predicted model Q6JXI5: TM-score 0.99, RMSD 0.75 Å
- 5DOK chain A against the predicted model Q6JXI5: TM-score 0.99, RMSD 0.75 Å
- 5DOI chain E against the predicted model Q6JXI5: TM-score 0.98, RMSD 0.47 Å
- 5DOI chain E against the predicted model Q6JXI5: TM-score 0.98, RMSD 0.47 Å
- 7UY5 chain J against the predicted model Q6JXI5: TM-score 0.86, RMSD 2.13 Å
- 7UY5 chain J against the predicted model Q6JXI5: TM-score 0.86, RMSD 2.13 Å
- 7UY7 chain B against the predicted model Q6JXI5: TM-score 0.52, RMSD 1.31 Å
- 7UY7 chain B against the predicted model Q6JXI5: TM-score 0.52, RMSD 1.31 Å
Elsewhere
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