UniProt Q6IQ49
Splicing regulator SDE2 (Q6IQ49)
Splicing regulator SDE2 (UniProt Q6IQ49): 3 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6IQ49
- Protein
- Splicing regulator SDE2
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
4 records of Q6IQ49 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | z | — | 2 (best 0.83) |
| 8RO2 | Integrative Structure of the human intron lariat Spliceosome (ILS'') | electron microscopy | z | — | — |
| 9FMD | Integrative model of the human post-catalytic spliceosome (P-complex) | electron microscopy | X | — | — |
| Q6IQ49 | AlphaFold monomer V2.0 prediction for replication stress response regulator SDE2 (Q6IQ49) | predicted | A | — | — |
Experiment against prediction
- 8C6J chain z against the predicted model Q6IQ49: TM-score 0.64, RMSD 1.65 Å
- 8RO2 chain z against the predicted model Q6IQ49: TM-score 0.59, RMSD 0.88 Å
- 9FMD chain X against the predicted model Q6IQ49: TM-score 0.51, RMSD 0.71 Å
Elsewhere
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