UniProt Q6H7M3
Copper-transporting ATPase HMA4 (Q6H7M3)
Copper-transporting ATPase HMA4 (UniProt Q6H7M3), EC 7.2.2.8: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q6H7M3
- Protein
- Copper-transporting ATPase HMA4
- EC
- 7.2.2.8
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 52 · 5 records with a druggable one
Structures
5 records of Q6H7M3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8Q73 | Copper-transporting ATPase HMA4 in E1 state apo | electron microscopy | A | — | 13 (best 0.71) |
| 8Q74 | Copper-transporting ATPase HMA4 in E1 state with Cu | electron microscopy | A | CU | 9 (best 0.68) |
| 8Q75 | Copper-transporting ATPase HMA4 in E2P state with AlF | electron microscopy | A | ALF, MG | 8 (best 0.70) |
| 8Q76 | Copper-transporting ATPase HMA4 in E2P state with BeF | electron microscopy | A | MG | 10 (best 0.67) |
| Q6H7M3 | AlphaFold monomer V2.0 prediction for copper-transporting ATPase HMA4 (Q6H7M3) | predicted | A | — | 12 (best 0.80) |
Ligands
Experiment against prediction
- 8Q73 chain A against the predicted model Q6H7M3: TM-score 0.87, RMSD 3.84 Å
- 8Q74 chain A against the predicted model Q6H7M3: TM-score 0.85, RMSD 4.18 Å
- 8Q75 chain A against the predicted model Q6H7M3: TM-score 0.66, RMSD 4.55 Å
- 8Q76 chain A against the predicted model Q6H7M3: TM-score 0.66, RMSD 4.68 Å
Elsewhere
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