UniProt Q6E434

Telomeric DNA-binding factor trf1 (Q6E434)

Telomeric DNA-binding factor trf1 (UniProt Q6E434): 4 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q6E434
Protein: Telomeric DNA-binding factor trf1
Experimental structures: 4
Predicted models: 1
Pockets: 18 · 2 records with a druggable one

Structures

5 records of Q6E434 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6K5S	Crystal structure of the Helical domain of S. pombe Tbf1	x-ray diffraction	A, B, C, D	—	9 (best 0.73)
6K5S	Crystal structure of the helical domain of S. pombe TBF1	x-ray diffraction	A, B, C, D	—	—
6K5U	Crystal structure of the myb domain of S. pombe Tbf1	x-ray diffraction	A, B	—	1 (best 0.29)
6K5U	Crystal structure of the myb domain of S. pombe TBF1	x-ray diffraction	A, B	—	—
Q6E434	AlphaFold monomer V2.0 prediction for telomeric DNA-binding factor TRF1 (Q6E434)	predicted	A	—	8 (best 0.67)

Experiment against prediction

6K5S chain B against the predicted model Q6E434: TM-score 0.97, RMSD 0.98 Å
6K5S chain B against the predicted model Q6E434: TM-score 0.97, RMSD 0.98 Å
6K5S chain A against the predicted model Q6E434: TM-score 0.97, RMSD 1.22 Å
6K5S chain A against the predicted model Q6E434: TM-score 0.97, RMSD 1.22 Å
6K5S chain D against the predicted model Q6E434: TM-score 0.96, RMSD 1.22 Å
6K5S chain D against the predicted model Q6E434: TM-score 0.96, RMSD 1.22 Å
6K5S chain C against the predicted model Q6E434: TM-score 0.95, RMSD 1.53 Å
6K5S chain C against the predicted model Q6E434: TM-score 0.95, RMSD 1.53 Å
6K5U chain A against the predicted model Q6E434: TM-score 0.76, RMSD 3.25 Å
6K5U chain A against the predicted model Q6E434: TM-score 0.76, RMSD 3.25 Å

Elsewhere

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