UniProt Q6CWM4
E3 ubiquitin-protein ligase BRE1 (Q6CWM4)
E3 ubiquitin-protein ligase BRE1 (UniProt Q6CWM4), EC 2.3.2.27: 1 experimental structure and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6CWM4
- Protein
- E3 ubiquitin-protein ligase BRE1
- EC
- 2.3.2.27
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
2 records of Q6CWM4 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W75 | Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form I | x-ray diffraction | C, D, E, F | — | 15 (best 0.73) |
| Q6CWM4 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase BRE1 (Q6CWM4) | predicted | A | — | — |
Experiment against prediction
- 7W75 chain C against the predicted model Q6CWM4: TM-score 0.71, RMSD 3.44 Å
- 7W75 chain E against the predicted model Q6CWM4: TM-score 0.68, RMSD 3.53 Å
- 7W75 chain F against the predicted model Q6CWM4: TM-score 0.49, RMSD 2.42 Å
- 7W75 chain D against the predicted model Q6CWM4: TM-score 0.44, RMSD 4.41 Å
Elsewhere
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