UniProt Q67PY4
Putative sphingosine-1-phosphate lyase (Q67PY4)
Putative sphingosine-1-phosphate lyase (UniProt Q67PY4): 12 experimental structures on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q67PY4
- Protein
- Putative sphingosine-1-phosphate lyase
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 13 · 1 record with a druggable one
Structures
12 records of Q67PY4 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3MAD | Crystal structure of StSPL (symmetric form) | x-ray diffraction | A, B | — | — |
| 3MAD | Crystal structure of stspl (symmetric form) | x-ray diffraction | A, B | — | — |
| 3MAF | Crystal structure of StSPL (asymmetric form) | x-ray diffraction | A, B | — | — |
| 3MAF | Crystal structure of stspl (asymmetric form) | x-ray diffraction | A, B | — | — |
| 3MAU | Crystal structure of StSPL in complex with phosphoethanolamine | x-ray diffraction | A, B, C, D | — | — |
| 3MAU | Crystal structure of stspl in complex with phosphoethanolamine | x-ray diffraction | A, B, C, D | — | — |
| 3MBB | Crystal structure of StSPL - apo form, after treatment with semicarbazide | x-ray diffraction | A, B | — | — |
| 3MBB | Crystal structure of stspl - apo form, after treatment with semicarbazide | x-ray diffraction | A, B | — | — |
| 5EUD | S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-di… | x-ray diffraction | A, B | PO4, 5S6 | — |
| 5EUD | S1P lyase bacterial surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1… | x-ray diffraction | A, B | — | — |
| 5EUE | S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-m… | x-ray diffraction | A, B | 5S5, PO4 | 13 (best 0.79) |
| 5EUE | S1P lyase bacterial surrogate bound to N-(2-((4-methoxy-2,5… | x-ray diffraction | A, B | — | — |
Ligands
- PO4 · Phosphate ion · in 2 records
- 5S5 · ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide · in 1 record
- 5S6 · ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide · in 1 record
Elsewhere
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