UniProt Q63787
Phosphatidylinositol 3-kinase regulatory alpha subunit (Q63787)
Phosphatidylinositol 3-kinase regulatory alpha subunit (UniProt Q63787): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q63787
- Protein
- Phosphatidylinositol 3-kinase regulatory alpha subunit
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
5 records of Q63787 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FU5 | NMR structure of the N-SH2 domain of the P85 subunit of PI3-kinase complexed to a doubly… | solution nmr | A | — | — |
| 1FU5 | NMR structure of the N-SH2 domain of the P85 subunit of PI3-kinase complexed to a doubly… | solution nmr | A | — | — |
| 1FU6 | NMR structure of the N-SH2 domain of the P85 subunit of PI3-kinase | solution nmr | A | — | — |
| 1FU6 | NMR structure of the N-SH2 domain of the P85 subunit of PI3-kinase | solution nmr | A | — | — |
| Q63787 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 3-kinase regulatory subunit alpha… | predicted | A | — | 3 (best 0.50) |
Experiment against prediction
- 1FU6 chain A against the predicted model Q63787: TM-score 0.69, RMSD 3.10 Å
- 1FU6 chain A against the predicted model Q63787: TM-score 0.69, RMSD 3.10 Å
- 1FU5 chain A against the predicted model Q63787: TM-score 0.65, RMSD 3.10 Å
- 1FU5 chain A against the predicted model Q63787: TM-score 0.65, RMSD 3.10 Å
Elsewhere
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