UniProt Q63472
Potassium voltage-gated channel subfamily H member 1 (Q63472)
Potassium voltage-gated channel subfamily H member 1 (UniProt Q63472): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 98 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q63472
- Protein
- Potassium voltage-gated channel subfamily H member 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 98 · 6 records with a druggable one
Structures
9 records of Q63472 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5K7L | Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel… | electron microscopy | A | NAG, Y01 | 7 (best 0.79) |
| 5K7L | Single particle cryo-EM structure of the voltage-gated K+ channel EAG1 bound to the channel… | electron microscopy | A | NAG, Y01 | — |
| 6PBX | Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound… | electron microscopy | A, C, E, G | — | 20 (best 0.80) |
| 6PBX | Single particle cryo-EM structure of the voltage-gated K+ channel EAG1 3-13 deletion mutant bound… | electron microscopy | A, C, E, G | — | — |
| 6PBY | Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound… | electron microscopy | A, C, E, G | — | 20 (best 0.78) |
| 6PBY | Single particle cryo-EM structure of the voltage-gated K+ channel EAG1 3-13 deletion mutant bound… | electron microscopy | A, C, E, G | — | — |
| 8EP0 | Eag Kv channel with voltage sensor in the intermediate conformation | electron microscopy | A, B, C, D | — | 20 (best 0.83) |
| 8EP1 | Eag Kv channel with voltage sensor in the down conformation | electron microscopy | A, D, C, B | — | 20 (best 0.83) |
| Q63472 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily H member 1 (Q63472) | predicted | A | — | 11 (best 0.72) |
Ligands
Experiment against prediction
- 6PBY chain E against the predicted model Q63472: TM-score 0.98, RMSD 1.36 Å
- 6PBY chain A against the predicted model Q63472: TM-score 0.98, RMSD 1.36 Å
- 6PBY chain A against the predicted model Q63472: TM-score 0.98, RMSD 1.36 Å
- 6PBY chain G against the predicted model Q63472: TM-score 0.98, RMSD 1.36 Å
- 6PBY chain C against the predicted model Q63472: TM-score 0.98, RMSD 1.36 Å
- 6PBX chain A against the predicted model Q63472: TM-score 0.97, RMSD 1.46 Å
- 6PBX chain A against the predicted model Q63472: TM-score 0.97, RMSD 1.46 Å
- 5K7L chain A against the predicted model Q63472: TM-score 0.97, RMSD 1.51 Å
- 5K7L chain A against the predicted model Q63472: TM-score 0.97, RMSD 1.51 Å
- 8EP0 chain A against the predicted model Q63472: TM-score 0.92, RMSD 2.62 Å
Elsewhere
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