UniProt Q62276
Mediator of RNA polymerase II transcription subunit 22 (Q62276)
Mediator of RNA polymerase II transcription subunit 22 (UniProt Q62276): 4 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q62276
- Protein
- Mediator of RNA polymerase II transcription subunit 22
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 7 · 3 records with a druggable one
Structures
5 records of Q62276 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | Q | — | 3 (best 0.81) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | Q | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | Q | — | 1 (best 0.86) |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | Q | — | 3 (best 0.88) |
| Q62276 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 22… | predicted | A | — | — |
Experiment against prediction
- 8T1L chain Q against the predicted model Q62276: TM-score 0.78, RMSD 2.73 Å
- 8T1I chain Q against the predicted model Q62276: TM-score 0.75, RMSD 2.63 Å
- 6W1S chain Q against the predicted model Q62276: TM-score 0.74, RMSD 2.76 Å
- 6W1S chain Q against the predicted model Q62276: TM-score 0.74, RMSD 2.76 Å
Elsewhere
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