UniProt Q61391
Neprilysin (Q61391)
Neprilysin (UniProt Q61391): 2 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q61391
- Protein
- Neprilysin
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
3 records of Q61391 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YVC | Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail | x-ray diffraction | D, E, F | — | — |
| 2YVC | Crystal structure of the radixin ferm domain complexed with the nep cytoplasmic tail | x-ray diffraction | D, E, F | — | — |
| Q61391 | AlphaFold monomer V2.0 prediction for neprilysin (Q61391) | predicted | A | — | 8 (best 0.66) |
Experiment against prediction
- 2YVC chain E against the predicted model Q61391: TM-score 0.67, RMSD 0.53 Å
- 2YVC chain E against the predicted model Q61391: TM-score 0.67, RMSD 0.53 Å
- 2YVC chain D against the predicted model Q61391: TM-score 0.60, RMSD 0.80 Å
- 2YVC chain D against the predicted model Q61391: TM-score 0.60, RMSD 0.80 Å
- 2YVC chain F against the predicted model Q61391: TM-score 0.23, RMSD 2.28 Å
- 2YVC chain F against the predicted model Q61391: TM-score 0.23, RMSD 2.28 Å
Elsewhere
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