UniProt Q61026
Nuclear receptor coactivator 2 (Q61026)
Nuclear receptor coactivator 2 (UniProt Q61026): 12 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q61026
- Protein
- Nuclear receptor coactivator 2
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
13 records of Q61026 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L2I | Human Estrogen Receptor alpha Ligand-binding Domain in Complex with… | x-ray diffraction | C, D | — | — |
| 1L2I | Human estrogen receptor alpha ligand-binding domain in complex with… | x-ray diffraction | C, D | — | — |
| 1OSV | Structural basis for bile acid binding and activation of the nuclear receptor fxr | x-ray diffraction | C, D, E | — | — |
| 1OSV | Structural basis for bile acid binding and activation of the nuclear receptor fxr | x-ray diffraction | C, D, E | — | — |
| 1WM0 | PPARgamma in complex with a 2-BABA compound | x-ray diffraction | Y | — | — |
| 1WM0 | Ppargamma in complex with a 2-baba compound | x-ray diffraction | Y | — | — |
| 3MNE | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation… | x-ray diffraction | B | — | — |
| 3MNE | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation… | x-ray diffraction | B | — | — |
| 3MNO | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S)… | x-ray diffraction | B | — | — |
| 3MNO | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S)… | x-ray diffraction | B | — | — |
| 3MNP | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, V708A… | x-ray diffraction | B | — | — |
| 3MNP | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, V708A… | x-ray diffraction | B | — | — |
| Q61026 | AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 2 (Q61026) | predicted | A | — | 3 (best 0.50) |
Experiment against prediction
- 1L2I chain C against the predicted model Q61026: TM-score 0.85, RMSD 0.28 Å
- 1L2I chain C against the predicted model Q61026: TM-score 0.85, RMSD 0.28 Å
- 3MNE chain B against the predicted model Q61026: TM-score 0.81, RMSD 0.80 Å
- 3MNE chain B against the predicted model Q61026: TM-score 0.81, RMSD 0.80 Å
- 3MNP chain B against the predicted model Q61026: TM-score 0.75, RMSD 0.62 Å
- 3MNP chain B against the predicted model Q61026: TM-score 0.75, RMSD 0.62 Å
- 3MNO chain B against the predicted model Q61026: TM-score 0.74, RMSD 0.71 Å
- 3MNO chain B against the predicted model Q61026: TM-score 0.74, RMSD 0.71 Å
- 1WM0 chain Y against the predicted model Q61026: TM-score 0.67, RMSD 0.98 Å
- 1WM0 chain Y against the predicted model Q61026: TM-score 0.67, RMSD 0.98 Å
Elsewhere
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