UniProt Q60795
Peptide from Nuclear factor erythroid 2-related factor 2 (Q60795)
Peptide from Nuclear factor erythroid 2-related factor 2 (UniProt Q60795): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q60795
- Protein
- Peptide from Nuclear factor erythroid 2-related factor 2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 8 records with a druggable one
Structures
9 records of Q60795 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X2R | Structural basis for the defects of human lung cancer somatic mutations in the repression activity… | x-ray diffraction | B | — | 1 (best 0.73) |
| 1X2R | Structural basis for the defects of human lung cancer somatic mutations in the repression activity… | x-ray diffraction | B | — | 1 (best 0.73) |
| 2DYH | Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2… | x-ray diffraction | B | — | 2 (best 0.73) |
| 2DYH | Crystal structure of the KEAP1 protein in complexed with the N-terminal region of the NRF2… | x-ray diffraction | B | — | 2 (best 0.73) |
| 3WN7 | Crystal Structure of Keap1 in Complex with the N-terminal region of the Nrf2 transcription factor | x-ray diffraction | B, M | — | 4 (best 0.74) |
| 3WN7 | Crystal structure of KEAP1 in complex with the N-terminal region of the NRF2 transcription factor | x-ray diffraction | B, M | — | 4 (best 0.74) |
| 7ECA | Crystal structure of the Keap1 complex with a peptide base on ETGE motif. | x-ray diffraction | B | SO4 | 1 (best 0.74) |
| 7ECA | Crystal structure of the KEAP1 complex with a peptide base on etge motif. | x-ray diffraction | B | SO4 | 1 (best 0.74) |
| Q60795 | AlphaFold monomer V2.0 prediction for nuclear factor erythroid 2-related factor 2 (Q60795) | predicted | A | — | 2 (best 0.33) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 2DYH chain B against the predicted model Q60795: TM-score 0.84, RMSD 0.22 Å
- 2DYH chain B against the predicted model Q60795: TM-score 0.84, RMSD 0.22 Å
- 1X2R chain B against the predicted model Q60795: TM-score 0.80, RMSD 0.47 Å
- 1X2R chain B against the predicted model Q60795: TM-score 0.80, RMSD 0.47 Å
- 7ECA chain B against the predicted model Q60795: TM-score 0.73, RMSD 0.53 Å
- 7ECA chain B against the predicted model Q60795: TM-score 0.73, RMSD 0.53 Å
- 3WN7 chain B against the predicted model Q60795: TM-score 0.42, RMSD 2.03 Å
- 3WN7 chain B against the predicted model Q60795: TM-score 0.42, RMSD 2.03 Å
Elsewhere
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